Effect of Food Inequality and Unstable Social Status on Myocardial Cells of Male Rabbits

Narjes Alsadat Nasabi | Majid Hassanpour-Ezatti | Soghrat Faghihzadeh | Taki Tiraihi | Ali Reza Safarpour | Mehrdad Roghani | Mohammadreza Vaezmahdavi | Shahnaz Mojarab

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URL :   http://research.shahed.ac.ir/WSR/WebPages/Report/PaperView.aspx?PaperID=85316
Date :  2010/02/14
Publish in :    World Applied Science Journal

Link :  http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.388.2178&rep=rep1&type=pdf
Keywords :Inequality, Rabbits

Abstract :

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Abstract: The relationship between socioeconomic status (SES) and health is well defined. Individuals with lower SES experience higher rate of mortality. Although life expectancies affected by poverty but the precise pathways that link socioeconomic status and health remain unclear. Lipofuscin is highly oxidized cross-linked aggregate consisting of oxidized protein and lipid clusters. This eminent terminal oxidation outcome accumulates within cells during aging process. Fifty four rabbits were randomly assigned into six groups of eight each. The first group (control G.) had free access to diet without any deprivation and changed place or room-mate. The second group had food deprivation, but did not change place or room-mate. The third group had food deprivation and changed place or room mate. The fourth group had similar condition with third group only five weeks then, conditions were the same to control group. The fifth group had condition similar to the third group, but its room was separated from other Groups. The sixth group had free access to diet without any deprivation but changed place or room-mate. All hearts were removed for histopathologic evaluation. Cross-sections of hearts were examined by light and electron microscopy for the presence of yellow-brown lipofuscin pigment granules (p0.05). We found that cardiac lipofuscin deposition increased under kind of stress that we applied. Our findings demonstrated that relation between environmental stresses such as inequality in food intake and social status instability with formations of lipofuscin pigments. Both stresses were probably created external source for oxidative stress in the myocardial muscle of left ventricular rabbits.