Shahed University

Data retrieved from in silico evaluation of vaccine potential of znud protein in acinetobacter baumannii

Iraj Rasooli | Maryam Mobarak | Shakiba Darvish

Date :  2020/07/20
Publish in :    Data in Brief

Keywords :Acinetobacter baumannii. ZnuD Physicochemical properties. Secondary structure

Abstract :
The nosocomial Acinetobacter baumannii is one of the most opportunistic pathogens that resists almost a broad range of antibiotics. Some bacterial metal acquisition systems are in- troduced as potential virulence factors in pathogen-host in- teraction. Bacterial zinc uptake (Znu) systems are critical transporters that play a major role in the survival of the pathogen and the establishment of infections. In silico char- acterization of ZnuD shows that it is an outer membrane pro- tein with high conservancy rates in most Acinetobacter bau- mannii strains. The in silico derived physicochemical prop- erties, structural and conserved immunoinformatic predic- tion data among Acinetobacter baumannii strains confirm that ZnuD belongs to Ton B dependent siderophore receptor fam- ilies and is considered as a potential vaccine candidate. A more detailed interpretation of the data presented in this ar- ticle is provided in “Identification and immunogenic proper- ties of recombinant ZnuD protein loops of Acinetobacter bau- mannii ”1 .