Prevalence of Micronutrient Deficiencies Prior to Bariatric Surgery: Tehran Obesity Treatment Study (TOTS)

Alireza Khlaj | Golaleh Asghari | Maryam Ghadimi | Maryam Mahdavi | Hossein Farhadnejad | Majid Valizadeh | Fereidoun Azizi | Maryam Barzin | Farhad Hosseinpanah

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URL :   http://research.shahed.ac.ir/WSR/WebPages/Report/PaperView.aspx?PaperID=137917
Date :  2018/03/08
Publish in :    Obesity Surgery: The Journal of Metabolic Surgery and Allied Care
DOI :  https://doi.org/10.1007/s11695-018-3187-y
Link :  http://dx.doi.org/10.1007/s11695-018-3187-y
Keywords : Bariatricsurgery .Metabolicsurgery .Micronutrientdeficiency .Prevalence

Abstract :

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Background Micronutrient deficiencies are major concerns after bariatric surgery, although these conditions often go undiagnosed pre-surgery. Objective Toassesspre-surgerymicronutrientstatusofanIranianpopulationofmorbidlyobesecandidatesofbariatricsurgeryin a cross-sectional study. Methods A cross-sectional analysis of 2008 candidates for bariatric surgery, aged 15–65 years, with either body mass index (BMI) ≥40 kg/m2 or 30 BMI 35 kg/m2 with a medical comorbidity was conducted. In order to determine the micronutrient status of participants, blood samples were collected to assess serum concentrations of vitamins (B12 and D), minerals (copper, calcium, phosphate, and zinc), and iron profiles (total iron binding capacity, iron concentration, ferritin, and iron saturation), according to standard protocol. Results The mean age and BMI of patients (79.3 female) were 37.8 years and 44.8 kg/m2, respectively. Deficiencies were foundfor25(OH)D(53.6),vitaminB12(34.4),serumiron(10.2),andlowlevelsofhemoglobin(16.6).Theprevalence of other deficiencies were all below 10. Body mass index had a negative correlation with iron, calcium, vitamin B12, and 25(OH) D and was positively correlated with copper. Conclusion Micronutrientdeficiencies,includingvitaminD,vitaminB12,andiron,arecommonlyfoundamongmorbidlyobese subjects who are potential candidates of bariatric surgery.