Shahed University


Marzieh Fotovvat | Tayebeh Radjabian | Azra Saboora

Date :  2017/05/10
Publish in :    6th National Congress on Medicinal Plants

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Keywords :HPLC, LC-MS, Tanshinones, Salvia Xanthocheilla

Abstract :
Genus Salvia is one of the largest members of the Labiatae family, comprising more than 900 species, many of them collected from the wild and a few of them cultivated 1. Over 58 species of the genus Salvia are found in Iran, 17 of which are endemic 2. It has been reported that tanshinones are the most abundant and important bioactive compounds in the roots some of Salvia species 3. Tanshinones, abietane-type norditerpenoidquinones, have been shown to exhibit diverse pharmacological activities, including, anti-platelet, cardioprotective, antibacterial, antioxidant, antidiabetes, anti-cancerand anti-inflammatory effects 3,4. This study was focused on identification and determination of some tanshinones in the extracts of roots of S.xantocheila present in Iranian flora by HPLC and LC-MS methods. Based on our results, there were tanshinone I, tanshinone IIA and cryptotanshinone in the roots of S.xantocheila. This is the first report about tanshinone composition of extract of S. xanthocheila and also the first report of these compositions in Iranian Salvia species. The natural occurrence of these compounds can be conclusive for the chemotaxonomic characterisation of this genus. In conclusion, some Iranian Salvia species could be introduced as new potent sources of rosmarinic acid and its derivatives. In the end, the roots of S. xantocheila could be introduced as new potent sources of tanshinone and its derivatives and also potent natural sources for medicinal, food and industrial purposes.

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